Multisite Validation Study to Determine Performance Characteristics of a 92-Gene Molecular Cancer Classifier

Accurate tumor classification is essential for cancer management as patient outcomes improve with use of site- and subtype-specific therapies. Current clinicopathologic evaluation is varied in approach, yet standardized diagnoses are critical for determining therapy. While gene expression–based cancer classifiers may potentially meet this need, imperative to determining their application to patient care is validation in rigorously designed studies. The study examined the performance of a 92-gene molecular classifier in a large multi-institution cohort.1

Available free from Clinical Cancer Research, an AACR publication.

1. Sarah E et al. Clin Cancer Res. 2012;18(14):3952–3960.

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